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Subjects assigned to the 50 mg and 70 mg retenue groups were titrated by 20 mg per week until they achieved their assigned mesure. The primary efficacy outcome was permutation in Ensemble Rangement from baseline to endpoint in investigator ratings on the ADHD Rating Scale (ADHD-RS), a measure of the core symptoms of ADHD. Endpoint was defined as the last post-randomization treatment week (i.e. Weeks 1 through 4) intuition which a valid classification was obtained. All Vyvanse retenue groups were superior to placebo in the primary efficacy outcome.
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